Just to provide some food for thought here is a list of many of the things a PWR is designed and operating crews are trained to prepare for:
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INSIDE PLANT LOCAL AREA EVACUATION SHUTDOWN FROM OUTSIDE THE CONTROL ROOM EARTHQUAKE OFFSITE POWER SYSTEM DISTURBANCES LOSS OF INSTRUMENT CONTROL SYSTEM AIR REACTOR COOLANT PUMP SEAL FAILURE LOSS OF SUPPORT SYSTEM COOLING SEVERE WEATHER CONDENSER SALT LEAK LOSS OF CONDENSER VACUUM EMERGENCY BORATION/INADVERTANT DILUTION OR BORATION MISALIGNED OR IMMOVABLE CONTROL ROD REACTOR COOLANT LEAK LOSS OF SHUTDOWN COOLING RECOVERY FROM INADVERTANT ENGINEERED SAFTY FEATURE ACTUATION REACTOR PROTECTION SYSTEM FAILURE LOSS OF VITAL AC INSTRUMENT POWER LOSS OF NON-VITAL AC INSTRUMENT POWER FUEL HANDLING ACCIDENTS LOSS OF SPENT FUEL POOL LEVEL OR COOLING FIRE LOSS OF CONTROL ROOM ANNUNCIATORS FEEDWATER CONTROL SYSTEM MALFUNCTION OPERATOR ACTIONS DURING SECURITY EVENTS LOSS OF POWER TO AN AC BUS PRESSURIZER PRESSURE OR LEVEL MALFUNCTION RAPID DOWN POWER
I would think about this list with the idea of being able to reply to any problem on it from a LFTR perspective. The NRC and other regulatory authorities will have a mindset based on these (semi) standard set of operational problems. We should be able to anticipate many questions.